Begin typing your search above and press return to search.
Geert Wilders
access_time 28 Nov 2023 4:50 AM GMT
Cusat tragedy: Let experience be a lesson
access_time 27 Nov 2023 4:00 AM GMT
A Constitution always in the making
access_time 27 Nov 2023 11:43 AM GMT
How long will the ceasefire last?
access_time 25 Nov 2023 5:56 AM GMT
The signal from Silkyara tunnel incident
access_time 24 Nov 2023 5:53 AM GMT
Schools breeding hatred
access_time 14 Sep 2023 10:37 AM GMT
access_time 16 Aug 2023 5:46 AM GMT
A Constitution always in the making
access_time 27 Nov 2023 11:43 AM GMT
Debunking myth of Israel’s existence
access_time 23 Oct 2023 7:01 AM GMT
Homechevron_rightTechnologychevron_rightIbuprofen in early...

Ibuprofen in early pregnancy may harm daughter's fertility

Ibuprofen in early pregnancy may harm daughters fertility

London: Women who consume commonly used Ibuprofen even for just two days during the first 24 weeks of their pregnancy may reduce their daughter's number of eggs, potentially affecting their fertility in the future, new research has warned.

The research carried out on human cells in the laboratory revealed that exposure to Ibuprofen during the crucial first three months of foetal development results in a "dramatic loss" of the germ cells that go into making the follicles from which female eggs develop.

The germ cells would either die or fail to grow and multiply at the usual rate.

"We found that two to seven days of exposure to Ibuprofen dramatically reduced the germ cell stockpile in human foetal ovaries during the first trimester of pregnancy and the ovaries did not recover fully from this damage," said Severine Mazaud-Guittot, a researcher at the National Institute for Health and Medical Research in France.

For the study, published in the journal Human Reproduction, the team exposed a part of the tissue from each of the 185 human foetuses between 7-12 weeks of development to Ibuprofen and kept the second part as the control.

They found that Ibuprofen crosses the placental barrier, with the foetus exposed to the same concentration of the drug as the mother.

Conversely, the tissue exposed to the drug for a week had approximately half the number of ovarian germ cells.

The researchers observed significant effects after seven days of exposure to the drug, with cell death seen as early as two days after treatment.

"This is the first study to look at the effects of Ibuprofen on the ovarian tissue of baby girls, and the first to show that it can cross the placental barrier during the first trimester of pregnancy, exposing the foetus to the drug," Mazaud-Guittot said.

Just as with any drug, Ibuprofen use should be restricted to the shortest duration and at the lowest dose necessary to achieve pain or fever relief, especially during pregnancy, the researchers suggested.

Show Full Article
Next Story